Think twice ask once: Cutting surgical waste

Once bitten, twice shy.

Better think before agreeing twice

Think twice before you tell

Answer to the Rhythm Puzzle At first glance the ECG looks very abnormal. The P-wave morphology is not compatible with sinus rhythm, the conduction intervals are normal, and the QRS complexes are very abnormal in amplitude (micro-voltages in the extremity leads). In lead II there is almost no signal at all. Althoughmicro-voltages in the extremity leads are a common feature in one of the most pre...

Once-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir

OBJECTIVE This multicenter, open-label, parallel-arm study compared the efficacy and safety of exenatide once weekly (EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas). RESEARCH DESIGN AND METHODS Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma gl...

Vertebroplasty for osteoporotic fracture? Think twice.

Think twice before recommending vertebroplasty (VP) for symptomatic osteoporotic compression fractures. New studies suggest that it has little benefit; thus, VP should be considered only after other, more conservative options fail.